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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
10
Human Site:
S424
Identified Species:
18.33
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
S424
L
G
Q
E
N
S
I
S
L
V
K
A
Y
W
N
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
S499
L
G
Q
E
N
S
I
S
L
V
K
A
Y
W
N
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
M381
H
V
A
F
R
L
T
M
P
S
P
M
P
E
Y
Dog
Lupus familis
XP_854792
605
67422
I425
A
L
G
Q
E
N
S
I
S
L
V
K
A
Y
W
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
Y416
S
I
S
L
V
K
A
Y
W
N
E
L
F
T
L
Rat
Rattus norvegicus
Q8VIJ4
590
65509
Y416
S
I
S
L
V
K
A
Y
W
N
E
L
F
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
W388
I
S
L
V
K
A
C
W
N
E
L
F
T
L
G
Chicken
Gallus gallus
O42101
501
57084
E328
R
S
S
I
F
F
R
E
L
K
V
D
D
Q
M
Frog
Xenopus laevis
Q66J63
637
70793
S458
L
G
Q
E
N
S
I
S
L
V
K
A
C
W
N
Zebra Danio
Brachydanio rerio
Q06725
411
45463
Q238
P
D
L
Q
I
T
D
Q
V
S
L
L
R
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
Q370
P
E
L
Q
V
T
D
Q
V
A
L
L
R
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
N417
Q
L
L
D
N
L
T
N
Q
M
A
M
G
M
E
Sea Urchin
Strong. purpuratus
Q26622
583
63834
L409
C
W
S
E
L
F
T
L
G
L
A
Q
C
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
0
0
N.A.
0
0
N.A.
0
6.6
93.3
0
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
100
0
26.6
N.A.
13.3
13.3
N.A.
13.3
6.6
93.3
20
N.A.
20
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
8
16
0
0
8
16
24
8
8
0
% A
% Cys:
8
0
0
0
0
0
8
0
0
0
0
0
16
0
0
% C
% Asp:
0
8
0
8
0
0
16
0
0
0
0
8
8
0
0
% D
% Glu:
0
8
0
31
8
0
0
8
0
8
16
0
0
8
8
% E
% Phe:
0
0
0
8
8
16
0
0
0
0
0
8
16
0
0
% F
% Gly:
0
24
8
0
0
0
0
0
8
0
0
0
8
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
16
0
8
8
0
24
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
16
0
0
0
8
24
8
0
0
0
% K
% Leu:
24
16
31
16
8
16
0
8
31
16
24
31
0
24
16
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
16
0
8
8
% M
% Asn:
0
0
0
0
31
8
0
8
8
16
0
0
0
0
24
% N
% Pro:
16
0
0
0
0
0
0
0
8
0
8
0
8
0
0
% P
% Gln:
8
0
24
24
0
0
0
16
8
0
0
8
0
8
8
% Q
% Arg:
8
0
0
0
8
0
8
0
0
0
0
0
16
0
0
% R
% Ser:
16
16
31
0
0
24
8
24
8
16
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
16
24
0
0
0
0
0
8
16
8
% T
% Val:
0
8
0
8
24
0
0
0
16
24
16
0
0
0
8
% V
% Trp:
0
8
0
0
0
0
0
8
16
0
0
0
0
24
8
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
0
0
16
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _